Pharmacokinetics and dosing

To best understand how to evaluate pharmacokinetics in peripartum women, it may be helpful to consider pregnancy and lactation as a continuum, as discussed ​​in this short presentation (20). The purpose of PK studies during pregnancy, as well as considerations around the study design, sample size and population PK modelling are described below, alongside considerations for neonates and infants.  

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Pregnancy
Fetal and neonatal PK